Cell Biol Chapter 7 outline
Intracellular membranes and intracellular traffic
I. ENDOPLASMIC RETICULUM (ER)
A) structure and characteristics
B) functions
1) smooth ER
a) synthesis of steroid hormones
b) hydroxylation reactions
c) synthesis of phospholipids
2) rough ER = site of protein synthesis (some)
II. The Golgi Complex (dictyosome in plants)
A) general functions
1) packaging of materials for secretion
2) processing of proteins
3) glycosylation of proteins and lipids
4) sorting of proteins for specific locations
B) structure
III. Biosynthesis of proteins
A) process – signal hypothesis
1) glycosylation
B) sorting - possibilities
1) different types of transport vesicles
2) tags on proteins specifying location
3) I cell disease
IV. Lysosomes
A) structure
1) primary lysosomes or protolysosomes
2) secondary lysosomes
B) functions
1) digestion of components brought into cell
2) recycling system
3) autolysis
C) lysosomal storage diseases
V. Movement of larger substances across membranes
A) endocytosis
1) pinocytosis
2) phagocytosis
3) receptor mediated endocytosis
B) exocytosis